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Synthesis and Biological Evaluation of Pyrroloindolines as Positive Allosteric Modulators of the α1β2γ2 GABA(A) Receptor
[Image: see text] γ-Aminobutyric acid type A (GABA(A)) receptors are key mediators of central inhibitory neurotransmission and have been implicated in several disorders of the central nervous system. Some positive allosteric modulators (PAMs) of this receptor provide great therapeutic benefits to pa...
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| Veröffentlicht in: | ACS Med Chem Lett |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2020
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7667864/ https://ncbi.nlm.nih.gov/pubmed/33214830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00340 |
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