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Enantioselective Synthesis of Pyrroloindolines by a Formal [3+2] Cycloaddition Reaction
(R)-BINOL•SnCl(4) was found to catalyze a formal [3+2] cycloaddition reaction between C(3)-substituted indoles and 2-amidoacrylates to provide pyrroloindolines. A variety of pyrroloindolines were prepared with high enantioselectivity in one step from simple precursors. This methodology is expected t...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222144/ https://ncbi.nlm.nih.gov/pubmed/20873714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107328g |
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