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Enantioselective Synthesis of Pyrroloindolines by a Formal [3+2] Cycloaddition Reaction

(R)-BINOL•SnCl(4) was found to catalyze a formal [3+2] cycloaddition reaction between C(3)-substituted indoles and 2-amidoacrylates to provide pyrroloindolines. A variety of pyrroloindolines were prepared with high enantioselectivity in one step from simple precursors. This methodology is expected t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Repka, Lindsay M., Ni, Jane, Reisman, Sarah E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222144/
https://ncbi.nlm.nih.gov/pubmed/20873714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107328g
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