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The free energy landscape in translational science: how can somatic mutations result in constitutive oncogenic activation?

The free energy landscape theory has transformed the field of protein folding. The significance of perceiving function in terms of conformational heterogeneity is gradually shifting the interest in the community from folding to function. From the free energy landscape standpoint the principles are u...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Phys Chem Chem Phys
Päätekijät: Tsai, Chung-Jung, Nussinov, Ruth
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667491/
https://ncbi.nlm.nih.gov/pubmed/24445437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cp54253j
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