GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery

Canonical Wnt signaling is emerging as a major regulator of endocytosis. Here, we report that Wnt-induced macropinocytosis is regulated through glycogen synthase kinase 3 (GSK3) and the β-catenin destruction complex. We find that mutation of Axin1, a tumor suppressor and component of the destruction...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Albrecht, Lauren V., Tejeda-Muñoz, Nydia, Bui, Maggie H., Cicchetto, Andrew C., Di Biagio, Daniele, Colozza, Gabriele, Schmid, Ernst, Piccolo, Stefano, Christofk, Heather R., De Robertis, Edward M.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666578/
https://ncbi.nlm.nih.gov/pubmed/32726636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107973
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料