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Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins
Canonical Wnt signaling is emerging as a major regulator of endocytosis. Wnt treatment markedly increased the endocytosis and degradation in lysosomes of BSA. In this study, we report that in addition to receptor-mediated endocytosis, Wnt also triggers the intake of large amounts of extracellular fl...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534993/ https://ncbi.nlm.nih.gov/pubmed/31061124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903506116 |
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