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Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins

Canonical Wnt signaling is emerging as a major regulator of endocytosis. Wnt treatment markedly increased the endocytosis and degradation in lysosomes of BSA. In this study, we report that in addition to receptor-mediated endocytosis, Wnt also triggers the intake of large amounts of extracellular fl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Tejeda-Muñoz, Nydia, Albrecht, Lauren V., Bui, Maggie H., De Robertis, Edward M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534993/
https://ncbi.nlm.nih.gov/pubmed/31061124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903506116
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