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WNT signaling suppresses oligodendrogenesis via Ngn2-dependent direct inhibition of Olig2 expression
Olig2 transcription factor is essential for the maintenance of neural progenitor cells (NPCs) in the pMN domain and their sequential specification into motor neurons (MNs) and oligodendrocyte precursor cells (OPCs). The expression of Olig2 rapidly declines in newly generated MNs. However, Olig2 expr...
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| Pubblicato in: | Mol Brain |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7666497/ https://ncbi.nlm.nih.gov/pubmed/33187539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00696-0 |
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