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Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells

Spinal motor neurons and oligodendrocytes are generated sequentially from a common pool of progenitors termed pMN cells. Olig2 is a bHLH-class transcription factor in pMN cells, but it has remained unclear how its transcriptional activity is modulated to first produce motor neurons and then oligoden...

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Detalhes bibliográficos
Main Authors: Lee, Soo-Kyung, Lee, Bora, Ruiz, Esmeralda C., Pfaff, Samuel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545894/
https://ncbi.nlm.nih.gov/pubmed/15655114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1257105
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