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Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1

Central nervous system injury and neurodegenerative diseases cause irreversible loss of neurons. Overexpression of exogenous specific transcription factors can reprogram somatic cells into functional neurons for regeneration and functional reconstruction. However, these practices are potentially pro...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Zhou, Meiling, Tao, Xiaoqing, Sui, Ming, Cui, Mengge, Liu, Dan, Wang, Beibei, Wang, Ting, Zheng, Yunjie, Luo, Juan, Mu, Yangling, Wan, Feng, Zhu, Ling-Qiang, Zhang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282467/
https://ncbi.nlm.nih.gov/pubmed/34171285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.05.020
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