Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1

Central nervous system injury and neurodegenerative diseases cause irreversible loss of neurons. Overexpression of exogenous specific transcription factors can reprogram somatic cells into functional neurons for regeneration and functional reconstruction. However, these practices are potentially pro...

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Publicat a:Stem Cell Reports
Autors principals: Zhou, Meiling, Tao, Xiaoqing, Sui, Ming, Cui, Mengge, Liu, Dan, Wang, Beibei, Wang, Ting, Zheng, Yunjie, Luo, Juan, Mu, Yangling, Wan, Feng, Zhu, Ling-Qiang, Zhang, Bin
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282467/
https://ncbi.nlm.nih.gov/pubmed/34171285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.05.020
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