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Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1
Central nervous system injury and neurodegenerative diseases cause irreversible loss of neurons. Overexpression of exogenous specific transcription factors can reprogram somatic cells into functional neurons for regeneration and functional reconstruction. However, these practices are potentially pro...
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| Pubblicato in: | Stem Cell Reports |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8282467/ https://ncbi.nlm.nih.gov/pubmed/34171285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.05.020 |
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