Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1

Central nervous system injury and neurodegenerative diseases cause irreversible loss of neurons. Overexpression of exogenous specific transcription factors can reprogram somatic cells into functional neurons for regeneration and functional reconstruction. However, these practices are potentially pro...

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Bibliografske podrobnosti
izdano v:Stem Cell Reports
Main Authors: Zhou, Meiling, Tao, Xiaoqing, Sui, Ming, Cui, Mengge, Liu, Dan, Wang, Beibei, Wang, Ting, Zheng, Yunjie, Luo, Juan, Mu, Yangling, Wan, Feng, Zhu, Ling-Qiang, Zhang, Bin
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282467/
https://ncbi.nlm.nih.gov/pubmed/34171285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.05.020
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