Guanine-rich sequences inhibit proofreading DNA polymerases

DNA polymerases with proofreading activity are important for accurate amplification of target DNA. Despite numerous efforts have been made to improve the proofreading DNA polymerases, they are more susceptible to be failed in PCR than non-proofreading DNA polymerases. Here we showed that proofreadin...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Zhu, Xiao-Jing, Sun, Shuhui, Xie, Binghua, Hu, Xuemei, Zhang, Zunyi, Qiu, Mengsheng, Dai, Zhong-Min
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923904/
https://ncbi.nlm.nih.gov/pubmed/27349576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28769
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