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Guanine-rich sequences inhibit proofreading DNA polymerases

DNA polymerases with proofreading activity are important for accurate amplification of target DNA. Despite numerous efforts have been made to improve the proofreading DNA polymerases, they are more susceptible to be failed in PCR than non-proofreading DNA polymerases. Here we showed that proofreadin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Xiao-Jing, Sun, Shuhui, Xie, Binghua, Hu, Xuemei, Zhang, Zunyi, Qiu, Mengsheng, Dai, Zhong-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923904/
https://ncbi.nlm.nih.gov/pubmed/27349576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28769
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