Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis

Long interspersed element-1 (LINE-1/L1) is the only autonomous transposable element in the human genome that currently mobilises in both germline and somatic tissues. Recent studies have identified correlations between altered retrotransposon expression and the fatal neurodegenerative disease amyotr...

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Dettagli Bibliografici
Pubblicato in:Mol Brain
Autori principali: Savage, Abigail L., Lopez, Ana Illera, Iacoangeli, Alfredo, Bubb, Vivien J., Smith, Bradley, Troakes, Claire, Alahmady, Nada, Koks, Sulev, Schumann, Gerald G., Al-Chalabi, Ammar, Quinn, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666467/
https://ncbi.nlm.nih.gov/pubmed/33187550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00694-2
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