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An Increased Burden of Highly Active Retrotransposition Competent L1s Is Associated with Parkinson’s Disease Risk and Progression in the PPMI Cohort

Long interspersed element-1 (LINE-1/L1s) contributes 17% of the human genome with more than 1 million elements present; however, fewer than 100 of these have evidence for being retrotransposition competent (RC). In addition to those RC-L1s present in the reference genome, there are a small number of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pfaff, Abigail L., Bubb, Vivien J., Quinn, John P., Koks, Sulev
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554759/
https://ncbi.nlm.nih.gov/pubmed/32911699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186562
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