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Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the APOE and MAPT Haplotypes

Genetic variations at the Apolipoprotein E (ApoE) and microtubule-associated protein tau (MAPT) loci have been implicated in multiple neurogenerative diseases, but their exact molecular mechanisms are unclear. In this study, we performed transcript level linear modelling using the blood whole transc...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Koks, Sulev, Pfaff, Abigail L., Bubb, Vivien J., Quinn, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999745/
https://ncbi.nlm.nih.gov/pubmed/33804213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12030423
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