Functional impacts of the ubiquitin–proteasome system on DNA damage recognition in global genome nucleotide excision repair

The ubiquitin–proteasome system (UPS) plays crucial roles in regulation of various biological processes, including DNA repair. In mammalian global genome nucleotide excision repair (GG-NER), activation of the DDB2-associated ubiquitin ligase upon UV-induced DNA damage is necessary for efficient reco...

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Udgivet i:Sci Rep
Main Authors: Sakai, Wataru, Yuasa-Sunagawa, Mayumi, Kusakabe, Masayuki, Kishimoto, Aiko, Matsui, Takeshi, Kaneko, Yuki, Akagi, Jun-ichi, Huyghe, Nicolas, Ikura, Masae, Ikura, Tsuyoshi, Hanaoka, Fumio, Yokoi, Masayuki, Sugasawa, Kaoru
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665181/
https://ncbi.nlm.nih.gov/pubmed/33184426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76898-2
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