Functional impacts of the ubiquitin–proteasome system on DNA damage recognition in global genome nucleotide excision repair

The ubiquitin–proteasome system (UPS) plays crucial roles in regulation of various biological processes, including DNA repair. In mammalian global genome nucleotide excision repair (GG-NER), activation of the DDB2-associated ubiquitin ligase upon UV-induced DNA damage is necessary for efficient reco...

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Publicado en:Sci Rep
Main Authors: Sakai, Wataru, Yuasa-Sunagawa, Mayumi, Kusakabe, Masayuki, Kishimoto, Aiko, Matsui, Takeshi, Kaneko, Yuki, Akagi, Jun-ichi, Huyghe, Nicolas, Ikura, Masae, Ikura, Tsuyoshi, Hanaoka, Fumio, Yokoi, Masayuki, Sugasawa, Kaoru
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665181/
https://ncbi.nlm.nih.gov/pubmed/33184426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76898-2
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