SUMOylation of xeroderma pigmentosum group C protein regulates DNA damage recognition during nucleotide excision repair

The xeroderma pigmentosum group C (XPC) protein complex is a key factor that detects DNA damage and initiates nucleotide excision repair (NER) in mammalian cells. Although biochemical and structural studies have elucidated the interaction of XPC with damaged DNA, the mechanism of its regulation in v...

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Publicado no:Sci Rep
Main Authors: Akita, Masaki, Tak, Yon-Soo, Shimura, Tsutomu, Matsumoto, Syota, Okuda-Shimizu, Yuki, Shimizu, Yuichiro, Nishi, Ryotaro, Saitoh, Hisato, Iwai, Shigenori, Mori, Toshio, Ikura, Tsuyoshi, Sakai, Wataru, Hanaoka, Fumio, Sugasawa, Kaoru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455304/
https://ncbi.nlm.nih.gov/pubmed/26042670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10984
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