SUMOylation of xeroderma pigmentosum group C protein regulates DNA damage recognition during nucleotide excision repair

The xeroderma pigmentosum group C (XPC) protein complex is a key factor that detects DNA damage and initiates nucleotide excision repair (NER) in mammalian cells. Although biochemical and structural studies have elucidated the interaction of XPC with damaged DNA, the mechanism of its regulation in v...

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Udgivet i:Sci Rep
Main Authors: Akita, Masaki, Tak, Yon-Soo, Shimura, Tsutomu, Matsumoto, Syota, Okuda-Shimizu, Yuki, Shimizu, Yuichiro, Nishi, Ryotaro, Saitoh, Hisato, Iwai, Shigenori, Mori, Toshio, Ikura, Tsuyoshi, Sakai, Wataru, Hanaoka, Fumio, Sugasawa, Kaoru
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455304/
https://ncbi.nlm.nih.gov/pubmed/26042670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10984
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