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Apelin-13 Protects Dopaminergic Neurons against Rotenone—Induced Neurotoxicity through the AMPK/mTOR/ULK-1 Mediated Autophagy Activation

Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Several brain–gut peptides are able to exert neuroprotective effects on the nigrostriatal dopaminergic system. Apelin-13 is a neuropeptide, conveying potential neuroprotec...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Chen, Peng, Wang, Youcui, Chen, Leilei, Song, Ning, Xie, Junxia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664695/
https://ncbi.nlm.nih.gov/pubmed/33171641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218376
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