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Apelin-13 Protects Dopaminergic Neurons against Rotenone—Induced Neurotoxicity through the AMPK/mTOR/ULK-1 Mediated Autophagy Activation

Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Several brain–gut peptides are able to exert neuroprotective effects on the nigrostriatal dopaminergic system. Apelin-13 is a neuropeptide, conveying potential neuroprotec...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Peng, Wang, Youcui, Chen, Leilei, Song, Ning, Xie, Junxia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664695/
https://ncbi.nlm.nih.gov/pubmed/33171641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218376
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