Allosterically Potentiated α7 Nicotinic Acetylcholine Receptors: Reduced Calcium Permeability and Current-Independent Control of Intracellular Calcium

The currents of α7 nicotinic acetylcholine receptors activated by acetylcholine (ACh) are brief. The channel has high permeability to calcium relative to monovalent cations and shows inward rectification. It has been previously noted that in the presence of positive allosteric modulators (PAMs), cur...

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Bibliografiset tiedot
Julkaisussa:Mol Pharmacol
Päätekijät: Miller, Douglas R., Khoshbouei, Habibeh, Garai, Sumanta, Cantwell, Lucas N., Stokes, Clare, Thakur, Ganesh, Papke, Roger L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2020
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662531/
https://ncbi.nlm.nih.gov/pubmed/33020143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000012
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