Deciphering Aspergillus fumigatus cyp51A-mediated triazole resistance by pyrosequencing of respiratory specimens

BACKGROUND: Infections caused by triazole drug-resistant Aspergillus fumigatus are an increasing problem. The sensitivity of standard culture is poor, abrogating susceptibility testing. Early detection of resistance can improve patient outcomes, yet tools for this purpose are limited. OBJECTIVES: To...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Novak-Frazer, Lilyann, Anees-Hill, Samuel P, Hassan, Darin, Masania, Rikesh, Moore, Caroline B, Richardson, Malcolm D, Denning, David W, Rautemaa-Richardson, Riina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662182/
https://ncbi.nlm.nih.gov/pubmed/32862231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa357
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