Deciphering Aspergillus fumigatus cyp51A-mediated triazole resistance by pyrosequencing of respiratory specimens

BACKGROUND: Infections caused by triazole drug-resistant Aspergillus fumigatus are an increasing problem. The sensitivity of standard culture is poor, abrogating susceptibility testing. Early detection of resistance can improve patient outcomes, yet tools for this purpose are limited. OBJECTIVES: To...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Novak-Frazer, Lilyann, Anees-Hill, Samuel P, Hassan, Darin, Masania, Rikesh, Moore, Caroline B, Richardson, Malcolm D, Denning, David W, Rautemaa-Richardson, Riina
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662182/
https://ncbi.nlm.nih.gov/pubmed/32862231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa357
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