Deciphering Aspergillus fumigatus cyp51A-mediated triazole resistance by pyrosequencing of respiratory specimens

BACKGROUND: Infections caused by triazole drug-resistant Aspergillus fumigatus are an increasing problem. The sensitivity of standard culture is poor, abrogating susceptibility testing. Early detection of resistance can improve patient outcomes, yet tools for this purpose are limited. OBJECTIVES: To...

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Detalles Bibliográficos
Publicado en:J Antimicrob Chemother
Autores principales: Novak-Frazer, Lilyann, Anees-Hill, Samuel P, Hassan, Darin, Masania, Rikesh, Moore, Caroline B, Richardson, Malcolm D, Denning, David W, Rautemaa-Richardson, Riina
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662182/
https://ncbi.nlm.nih.gov/pubmed/32862231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa357
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