Fidelity of human ovarian cancer patient-derived xenografts in a partially humanized mouse model for preclinical testing of immunotherapies

BACKGROUND: Immune checkpoint blockers (ICBs) have been approved by the Food and Drug Administration to be used alone in front-line therapies or in combination with other regimens for certain advanced cancers. Since ICB only works in a subset of patients and has limited efficacy in treating ovarian...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Odunsi, Adekunle, McGray, A J Robert, Miliotto, Anthony, Zhang, Yali, Wang, Jianming, Abiola, Adebukola, Eppolito, Cheryl, Huang, Ruea-Yea
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661374/
https://ncbi.nlm.nih.gov/pubmed/33177175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001237
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