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Leveraging functional annotation to identify genes associated with complex diseases
To increase statistical power to identify genes associated with complex traits, a number of transcriptome-wide association study (TWAS) methods have been proposed using gene expression as a mediating trait linking genetic variations and diseases. These methods first predict expression levels based o...
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| Publicado no: | PLoS Comput Biol |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7660930/ https://ncbi.nlm.nih.gov/pubmed/33137096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008315 |
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