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Leveraging functional annotations in genetic risk prediction for human complex diseases

Genetic risk prediction is an important goal in human genetics research and precision medicine. Accurate prediction models will have great impacts on both disease prevention and early treatment strategies. Despite the identification of thousands of disease-associated genetic variants through genome...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Hu, Yiming, Lu, Qiongshi, Powles, Ryan, Yao, Xinwei, Yang, Can, Fang, Fang, Xu, Xinran, Zhao, Hongyu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481142/
https://ncbi.nlm.nih.gov/pubmed/28594818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005589
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