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Leveraging functional annotations in genetic risk prediction for human complex diseases

Genetic risk prediction is an important goal in human genetics research and precision medicine. Accurate prediction models will have great impacts on both disease prevention and early treatment strategies. Despite the identification of thousands of disease-associated genetic variants through genome...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Hu, Yiming, Lu, Qiongshi, Powles, Ryan, Yao, Xinwei, Yang, Can, Fang, Fang, Xu, Xinran, Zhao, Hongyu
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481142/
https://ncbi.nlm.nih.gov/pubmed/28594818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005589
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