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Leveraging functional annotations in genetic risk prediction for human complex diseases

Genetic risk prediction is an important goal in human genetics research and precision medicine. Accurate prediction models will have great impacts on both disease prevention and early treatment strategies. Despite the identification of thousands of disease-associated genetic variants through genome...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Hu, Yiming, Lu, Qiongshi, Powles, Ryan, Yao, Xinwei, Yang, Can, Fang, Fang, Xu, Xinran, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481142/
https://ncbi.nlm.nih.gov/pubmed/28594818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005589
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