The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation

Loss of von Hippel-Lindau protein pVHL function promotes VHL diseases, including sporadic and inherited clear cell Renal Cell Carcinoma (ccRCC). Mechanisms controlling pVHL function and regulation, including folding and stability, remain elusive. Here, we have identified the conserved cochaperone pr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Chesnel, Franck, Couturier, Anne, Alusse, Adrien, Gagné, Jean-Philippe, Poirier, Guy G., Jean, Dominique, Boisvert, François-Michel, Hascoet, Pauline, Paillard, Luc, Arlot-Bonnemains, Yannick, Le Goff, Xavier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660911/
https://ncbi.nlm.nih.gov/pubmed/33137104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009183
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge