The von Hippel–Lindau tumour suppressor gene: uncovering the expression of the pVHL172 isoform

BACKGROUND: The von Hippel–Lindau (VHL) gene encodes two mRNA variants. Variant 1 encodes two protein isoforms, pVHL(213) and pVHL(160), that have been extensively documented in the literature. Variant 2 is produced by alternative splicing of exon 2 and encodes a pVHL isoform of 172 amino acids with...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Chesnel, F, Hascoet, P, Gagné, J P, Couturier, A, Jouan, F, Poirier, G G, Le Goff, C, Vigneau, C, Danger, Y, Verite, F, Le Goff, X, Arlot-Bonnemains, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506380/
https://ncbi.nlm.nih.gov/pubmed/26035699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.189
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