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In vivo miRNA knockout screening identifies miR-190b as a novel tumor suppressor
MicroRNAs (miRNAs) play important roles in the development of various cancers including lung cancer which is one of the devastating diseases worldwide. How miRNAs function in de novo lung tumorigenesis remains largely unknown. We here developed a CRISPR/Cas9-mediated dual guide RNA (dgRNA) system to...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7660552/ https://ncbi.nlm.nih.gov/pubmed/33137086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009168 |
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