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Nuclear translocation of pro‐amphiregulin induces chemoresistance in gastric cancer

Amphiregulin (AR) is derived from a membrane‐anchored form (proAR) by ectodomain shedding, and is a ligand that activates epidermal growth factor receptor (EGFR). We have recently shown that proAR translocates from the plasma membrane to the nucleus after truncation of 11 amino acids at the C‐termin...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Yoshida, Michihiro, Shimura, Takaya, Fukuda, Shinji, Mizoshita, Tsutomu, Tanida, Satoshi, Kataoka, Hiromi, Kamiya, Takeshi, Nakazawa, Takahiro, Higashiyama, Shigeki, Joh, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659380/
https://ncbi.nlm.nih.gov/pubmed/22320154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02204.x
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