Nuclear translocation of pro‐amphiregulin induces chemoresistance in gastric cancer

Amphiregulin (AR) is derived from a membrane‐anchored form (proAR) by ectodomain shedding, and is a ligand that activates epidermal growth factor receptor (EGFR). We have recently shown that proAR translocates from the plasma membrane to the nucleus after truncation of 11 amino acids at the C‐termin...

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Dades bibliogràfiques
Publicat a:Cancer Sci
Autors principals: Yoshida, Michihiro, Shimura, Takaya, Fukuda, Shinji, Mizoshita, Tsutomu, Tanida, Satoshi, Kataoka, Hiromi, Kamiya, Takeshi, Nakazawa, Takahiro, Higashiyama, Shigeki, Joh, Takashi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2012
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659380/
https://ncbi.nlm.nih.gov/pubmed/22320154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02204.x
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