Nuclear translocation of pro‐amphiregulin induces chemoresistance in gastric cancer

Amphiregulin (AR) is derived from a membrane‐anchored form (proAR) by ectodomain shedding, and is a ligand that activates epidermal growth factor receptor (EGFR). We have recently shown that proAR translocates from the plasma membrane to the nucleus after truncation of 11 amino acids at the C‐termin...

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Bibliografische gegevens
Gepubliceerd in:Cancer Sci
Hoofdauteurs: Yoshida, Michihiro, Shimura, Takaya, Fukuda, Shinji, Mizoshita, Tsutomu, Tanida, Satoshi, Kataoka, Hiromi, Kamiya, Takeshi, Nakazawa, Takahiro, Higashiyama, Shigeki, Joh, Takashi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2012
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659380/
https://ncbi.nlm.nih.gov/pubmed/22320154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02204.x
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