Differential MyD88/IRAK4 requirements for cross‐priming and tumor rejection induced by heat shock protein 70‐model antigen fusion protein

Priming of CD8(+) T cells requires two signals, one produced by T‐cell receptor recognition of antigen, and a second that is often provided by the innate immune response. In this context, antigens non‐covalently or covalently associated with heat shock proteins (HSP) are internalized and processed i...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Mizukami, Shusaku, Kajiwara, Chiaki, Tanaka, Masato, Kaisho, Tsuneyasu, Udono, Heiichiro
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659281/
https://ncbi.nlm.nih.gov/pubmed/22320267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02233.x
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