Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency

Autosomal recessive interleukin-1 receptor-associated kinase (IRAK)-4 and myeloid differentiation factor (MyD)88 deficiencies impair Toll-like receptor (TLR)- and interleukin-1 receptor-mediated immunity. We documented the clinical features and outcome of 48 patients with IRAK-4 deficiency and 12 pa...

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Main Authors: Picard, Capucine, von Bernuth, Horst, Ghandil, Pegah, Chrabieh, Maya, Levy, Ofer, Arkwright, Peter D., McDonald, Douglas, Geha, Raif S., Takada, Hidetoshi, Krause, Jens C., Creech, C. Buddy, Ku, Cheng-Lung, Ehl, Stephan, Maŕodi, Ĺaszĺo, Al-Muhsen, Saleh, Al-Hajjar, Sami, Al-Ghonaium, Abdulaziz, Day-Good, Noorbibi K., Holland, Steven M., Gallin, John, Chapel, Helen, Speert, David P., Rodriguez-Gallego, Carlos, Colino, Elena, Garty, Ben-Zion, Roifman, Chaim, Hara, Toshiro, Yoshikawa, Hideto, Nonoyama, Shigeaki, Domachowske, Joseph, Issekutz, Andrew C., Tang, Mimi, Smart, Joanne, Zitnik, Simona Eva, Hoarau, Cyrille, Kumararatne, Dinakantha, Thrasher, Adrian, Davies, E. Graham, Bethune, Claire, Sirvent, Nicolas, de Ricaud, Dominique, Camcioglu, Yildiz, Vasconcelos, J́ulia, Guedes, Margarida, Vitor, Artur Bonito, Rodrigo, Carlos, AlmaŸan, Francisco, Ḿendez, Maria, Aŕostegui, Juan Ignacio, Alsina, Laia, Fortuny, Claudia, Reichenbach, Janine, Verbsky, James W, Bossuyt, Xavier, Doffinger, Rainer, Abel, Laurent, Puel, Anne, Casanova, Jean-Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103888/
https://ncbi.nlm.nih.gov/pubmed/21057262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0b013e3181fd8ec3
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