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Impaired T cell receptor activation in Interleukin-1 Receptor-associated Kinase-4-deficient patients
BACKGROUND: Interleukin-1 receptor associated kinase-4 (IRAK-4) is an effector of the Toll-like receptor and interleukin-1 receptor pathways, which plays a critical role in innate immune responses. The role of IRAK-4 in adaptive immune functions in humans is incompletely understood. OBJECTIVE: To ev...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917474/ https://ncbi.nlm.nih.gov/pubmed/20621347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.05.013 |
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