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Homodimerization of the human interleukin 4 receptor α chain induces Cɛ germline transcripts in B cells in the absence of the interleukin 2 receptor γ chain
The cytokines interleukin (IL)-4 and IL-13 play a critical role in inducing Cɛ germline transcripts and IgE isotype switching in human B cells. The IL-4 receptor (IL-4R) in B cells is composed of two chains, the IL-4-binding IL-4Rα chain, which is shared with the IL-13R, and the IL-2Rγ (γc) chain, w...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences of the USA
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20872/ https://ncbi.nlm.nih.gov/pubmed/9159166 |
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