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Structure of Germline Immunoglobulin Heavy-Chain γ1 Transcripts in Interleukin 4 Treated Mouse Spleen Cells

Antibody class switching is mediated by a DNA recombination event that replaces the Cμ gene with one of the other heavy (H) chain constant region (C(H)) genes located 3' to the Cμ gene. The regulation of this process is essential to the immune response because different C(H) regions provide dif...

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Autors principals: Xu, Minzhen, Stavnezer, Janet
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275814/
https://ncbi.nlm.nih.gov/pubmed/1726553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1990/47659
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