Structure and expression of murine germ-line immunoglobulin epsilon heavy chain transcripts induced by interleukin 4.
The murine lymphokine, interleukin 4 (IL-4) is able to specifically promote isotype switching to IgG1 and IgE in cultures of mitogen-stimulated B cells. Emerging evidence suggests that germ-line immunoglobulin heavy chain gene transcription may direct switching by modulating switch-region accessibil...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53519/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2106137/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1581 |
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