Retinoblastoma gene‐independent G (1) phase arrest by flavone, phosphatidylinositol 3‐kinase inhibitor, and histone deacetylase inhibitor

In most human malignant tumors, retinoblastoma tumor‐suppressor gene (RB) product is inactivated by phosphorylation. Therefore, cancer preventive agents or molecular‐targeting agents can inhibit the tumor growth at G (1) phase through RB reactivation. However, little is known about the effectiveness...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Tomosugi, Mitsuhiro, Sowa, Yoshihiro, Yasuda, Shusuke, Tanaka, Ryoichi, te Riele, Hein, Ikawa, Haruna, Koyama, Makoto, Sakai, Toshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659262/
https://ncbi.nlm.nih.gov/pubmed/22957647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12012
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