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The retinoblastoma protein: multitasking to suppress tumorigenesis
Tumor suppressor activity of the retinoblastoma protein pRB is preserved despite loss of interaction with E2F transcription factors (E2F) or proteins harboring a leucine-x-cysteine-x-glutamic acid motif (LxCxE, where x is any amino acid). This indicates that pRB uses several parallel pathways to sup...
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Publicado no: | Mol Cell Oncol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905230/ https://ncbi.nlm.nih.gov/pubmed/27308398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.968062 |
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