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SB365 inhibits angiogenesis and induces apoptosis of hepatocellular carcinoma through modulation of PI3K/Akt/mTOR signaling pathway

Identification of small molecules that safely inhibit cancer progression is critical for cancer therapeutics. Saponins exhibit cytostatic and cytotoxic activity against various cancer cells, but the mechanism is not well understood. Here, we investigated whether saponin D (designated SB365), an acti...

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Detalles Bibliográficos
Publicado en:Cancer Sci
Main Authors: Hong, Sang‐Won, Jung, Kyung Hee, Lee, Hee‐Seung, Choi, Myung‐Joo, Son, Mi Kwon, Zheng, Hong‐Mei, Hong, Soon‐Sun
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659253/
https://ncbi.nlm.nih.gov/pubmed/22909393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02409.x
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