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SB365 inhibits angiogenesis and induces apoptosis of hepatocellular carcinoma through modulation of PI3K/Akt/mTOR signaling pathway

Identification of small molecules that safely inhibit cancer progression is critical for cancer therapeutics. Saponins exhibit cytostatic and cytotoxic activity against various cancer cells, but the mechanism is not well understood. Here, we investigated whether saponin D (designated SB365), an acti...

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Bibliografische gegevens
Gepubliceerd in:Cancer Sci
Hoofdauteurs: Hong, Sang‐Won, Jung, Kyung Hee, Lee, Hee‐Seung, Choi, Myung‐Joo, Son, Mi Kwon, Zheng, Hong‐Mei, Hong, Soon‐Sun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659253/
https://ncbi.nlm.nih.gov/pubmed/22909393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02409.x
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