SB365 inhibits angiogenesis and induces apoptosis of hepatocellular carcinoma through modulation of PI3K/Akt/mTOR signaling pathway

Identification of small molecules that safely inhibit cancer progression is critical for cancer therapeutics. Saponins exhibit cytostatic and cytotoxic activity against various cancer cells, but the mechanism is not well understood. Here, we investigated whether saponin D (designated SB365), an acti...

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Detaylı Bibliyografya
Yayımlandı:Cancer Sci
Asıl Yazarlar: Hong, Sang‐Won, Jung, Kyung Hee, Lee, Hee‐Seung, Choi, Myung‐Joo, Son, Mi Kwon, Zheng, Hong‐Mei, Hong, Soon‐Sun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2012
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659253/
https://ncbi.nlm.nih.gov/pubmed/22909393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02409.x
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