Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts

Thioridazine, a member of the phenothiazine family, is a powerful anti-anxiety and anti-psychotic drug. It can also suppress the growth of several types of tumor in vitro. In the current study, we evaluated the direct anti-tumor and anti-angiogenic effects of thioridazine in vivo. The injection of t...

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Detalhes bibliográficos
Main Authors: Park, Mi Sun, Dong, Seung Myung, Kim, Boh-Ram, Seo, Seung Hee, Kang, Sokbom, Lee, Eun-Ju, Lee, Seung-Hoon, Rho, Seung Bae
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148111/
https://ncbi.nlm.nih.gov/pubmed/24952635
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