Loss of 5‐hydroxymethylcytosine is accompanied with malignant cellular transformation

Dysregulated DNA methylation followed by abnormal gene expression is an epigenetic hallmark in cancer. DNA methylation is catalyzed by DNA methyltransferases, and the aberrant expression or mutations of DNA methyltransferase genes are found in human neoplasm. The enzymes for demethylating 5‐methylcy...

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Bibliografski detalji
Izdano u:Cancer Sci
Glavni autori: Kudo, Yotaro, Tateishi, Keisuke, Yamamoto, Keisuke, Yamamoto, Shinzo, Asaoka, Yoshinari, Ijichi, Hideaki, Nagae, Genta, Yoshida, Haruhiko, Aburatani, Hiroyuki, Koike, Kazuhiko
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2012
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659252/
https://ncbi.nlm.nih.gov/pubmed/22320381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02213.x
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