Loss of 5‐hydroxymethylcytosine is accompanied with malignant cellular transformation

Dysregulated DNA methylation followed by abnormal gene expression is an epigenetic hallmark in cancer. DNA methylation is catalyzed by DNA methyltransferases, and the aberrant expression or mutations of DNA methyltransferase genes are found in human neoplasm. The enzymes for demethylating 5‐methylcy...

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Bibliografische gegevens
Gepubliceerd in:Cancer Sci
Hoofdauteurs: Kudo, Yotaro, Tateishi, Keisuke, Yamamoto, Keisuke, Yamamoto, Shinzo, Asaoka, Yoshinari, Ijichi, Hideaki, Nagae, Genta, Yoshida, Haruhiko, Aburatani, Hiroyuki, Koike, Kazuhiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2012
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659252/
https://ncbi.nlm.nih.gov/pubmed/22320381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02213.x
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