Loss of 5‐hydroxymethylcytosine is accompanied with malignant cellular transformation

Dysregulated DNA methylation followed by abnormal gene expression is an epigenetic hallmark in cancer. DNA methylation is catalyzed by DNA methyltransferases, and the aberrant expression or mutations of DNA methyltransferase genes are found in human neoplasm. The enzymes for demethylating 5‐methylcy...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kudo, Yotaro, Tateishi, Keisuke, Yamamoto, Keisuke, Yamamoto, Shinzo, Asaoka, Yoshinari, Ijichi, Hideaki, Nagae, Genta, Yoshida, Haruhiko, Aburatani, Hiroyuki, Koike, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659252/
https://ncbi.nlm.nih.gov/pubmed/22320381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02213.x
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