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Loss of 5‐hydroxymethylcytosine is accompanied with malignant cellular transformation
Dysregulated DNA methylation followed by abnormal gene expression is an epigenetic hallmark in cancer. DNA methylation is catalyzed by DNA methyltransferases, and the aberrant expression or mutations of DNA methyltransferase genes are found in human neoplasm. The enzymes for demethylating 5‐methylcy...
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| Publié dans: | Cancer Sci |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659252/ https://ncbi.nlm.nih.gov/pubmed/22320381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02213.x |
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